Clinical Research of Ingredients

Levean - Backed by Real Science

The individual ingredients we selected for use in Levean are all well-known in the health community for their benefits - but also often backed by clinical studies and trials. 

To learn more, we encourage our customers to not just take our word for it - but to educate and read for themselves. Here are just a few resources and studies from the US Government's National Library of Medicine and other recognized medical science journals - on each one of Levean's ingredients: 


"Forskolin is a diterpene derived from the plant Coleus forskohlii. Forskolin activates adenylate cyclase, which increases intracellular cAMP levels. The antioxidant and antiinflammatory action of forskolin is due to inhibition of macrophage activation with a subsequent reduction in thromboxane B2 and superoxide levels. These characteristics have made forskolin an effective medication for heart disease, hypertension, diabetes, and asthma"

- International Journal of Medical Sciences, 11 Mar 2014

Study showing Forskolin's role in regulating hypertension (high blood pressure)

Study showing Forskolin's role in insulation regulation with regards to body weight

Study finding Forskolin's ability to "positively influence the loss and management of overall body weight possibly as a means of maintaining weight after weight loss"

Study showing Forskolin's role in promoting nerve repair by increasing concentrations of nerve messengers in the brain, known as cAMP

Study on Forskolin's possible ability to restore or protect neurological pathways and in the future aid with diseases such as Alzheimer's.

More Forskolin research at


"There have been at least eight clinical studies conducted in over 180 humans using astaxanthin to assess its safety, bioavailability and clinical aspects relevant to oxidative stress, inflammation or the cardiovascular system. There have been no adverse outcomes reported. Studies have demonstrated reduced markers of oxidative stress and inflammation and improved blood rheology. A larger number of experimental studies have been performed using astaxanthin. In particular, studies in a variety of animals using a model of myocardial ischemia and reperfusion have demonstrated protective effects from prior administration of astaxanthin both intravenously and orally."

- School of Human Movement Studies & School of Medicine, The University of Queensland, Queensland, Australia, July 2005

Study on Astaxanthin's anti-inflammatory benefits

Study on Astaxanthin's role in skin health, repair and dermatology

Neuroprotective mechanisms of Astaxanthin: a potential therapeutic role in preserving cognitive function in age and neurodegeneration

Study: Astaxanthin in Exercise Metabolism, Performance and Recovery

Astaxanthin in cardiovascular health and disease: mechanisms of action, therapeutic merits, and knowledge gaps

Neuroprotective role of Astaxanthin

More Astaxanthin research at


"Curcumin has received worldwide attention for its multiple health benefits, which appear to act primarily through its anti-oxidant and anti-inflammatory mechanisms. Research suggests that curcumin can help in the management of oxidative and inflammatory conditions, metabolic syndrome, arthritis, anxiety, and hyperlipidemia. It may also help in the management of exercise-induced inflammation and muscle soreness, thus enhancing recovery and subsequent performance in active people. In addition, a relatively low dose can provide health benefits for people that do not have diagnosed health conditions."

- Central Michigan University, 2017

Copyright (C) Advanced Biomedical Research, 2018

Study on Curcumin's role in reducing inflammation, arthritis relief, and more.

Study showing Curcumin's benefits relating to irritable bowel syndrome (IBD), ulcerative colitis, Thalassemia, and cholesterol regulating properties.

Study on Curcumin's role in lowering the symptoms of arthritis

Antioxidant And Anti-Inflammatory Properties Of Curcumin

Role of Curcumin in Disease Prevention and Treatment

More Curcumin research at

CoQ 10

"As most cellular functions are dependent on an adequate supply of Adenosine triphosphate (ATP), CoQ10 is essential for the health of virtually all human tissues and organs. Coenzyme Q10 is one of the most significant lipid antioxidants, which prevents the generation of free radicals and modifications of proteins, lipids, and DNA. In many disease conditions connected with increased generation and the action of reactive oxygen species (ROS), the concentration of coenzyme Q10 in the human body decreases and the deficiency of coenzyme Q10 leads to the dysfunction of the respiratory chain, which is due to the insufficient production of highly energetic compounds, which decrease the efficiency of cells"

- Journal of Pharmacy & BioAllied Sciences, 2011

CoQ 10 - the Essential Nutrient

Study on CoQ 10's role in anti-aging and disease prevention

Role of Coenzyme Q10 as an antioxidant and bioenergizer in periodontal diseases

Study showing CoQ 10's anti-inflammatory properties

More CoQ 10 research at


"Chromium is an essential mineral that appears to have a beneficial role in the regulation of insulin action and its effects on carbohydrate, protein and lipid metabolism. Chromium is an important factor for enhancing insulin activity. Studies show that people with type 2 diabetes have lower blood levels of chromium than those without the disease. Insulin resistance is the common denominator in a cluster of cardiovascular disease risk factors."


Study showing Chromium's role in insulin / blood sugar, and cholesterol regulation

Study on Chromium's benefit in glucose, insulin and cardiovascular health

Study on Chromium's role in Diabetes Type 2 prevention and insulin resistance

Government fact sheet on Chromium supplementation benefits

Study on Chromium's role in appetite suppression and food cravings for weight loss

Study on Chromium's role in depression and carbohydrate cravings

More Chromium research at


"Resveratrol is a potent member of the class of natural, plant-derived chemicals known as polyphenols. These help explain in part why a diet high in fruit and vegetables confers health benefits and are associated with reduced risk of common complex conditions such as cardiovascular disease, cancer, diabetes, and Alzheimer’s disease. While a healthy diet and lifestyle is strongly recommended in prevention of such conditions, the future bodes well for the use of resveratrol and analogues of higher potency than the natural form for treatment of diseases that afflict humans, particularly as they age."

- DovePress, Clinical Interventions in Aging

Resveratrol in prevention and treatment of common clinical conditions of aging

Study on Resveratrol - A review of clinical trials

Multiple health benefits of Resveratrol, a study

Study on Resveratrol's positive effects on gut bacteria and stem cell proliferation, anti aging benefits, anti-inflammatory properties, and more.

More Resveratrol research at

Vitamin D3

"Vitamin D sufficiency is required for optimal health. The conditions with strong evidence for a protective effect of vitamin D include several bone diseases, muscle weakness, more than a dozen types of internal cancers, multiple sclerosis, and type 1 diabetes mellitus. There is also weaker evidence for several other diseases and conditions. There are good reasons that vitamin D sufficiency be maintained during all stages of life, from fetal development to old age."


Copyright (C) - HHS Public Access, Aarash Hossein-nezhad MD, PHD, and Michael F Holick PHD, MD

Study on Vitamin D3's many important roles and health benefits

More Vitamin D3 research at